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Togetter's awesome widget is not allowed to be copied, pinned, or embedded without the terms of use.Heart failure and beta adrenergic activation: reduced norepinephrine and up-regulated serotonin receptors.
After myocardial infarction (MI) neurohumoral activation, primarily by elevated plasma catecholamines, leads to heart failure (HF). HF and cardiorenal syndrome share common mechanisms, such as impaired nitric oxide (NO) and endothelin production, but HF is more poorly regulated by the neurohormonal system. The aim was to study the changes in receptors that mediate neurohormonal activity in HF. Twenty-six patients with HF after MI were compared with 26 controls (C) matched for age, sex and body surface area. At baseline, norepinephrine (NE), NO and serum aldosterone, and at 4 months after MI, NE, NO, neurohumoral factors and receptor subtypes were studied. Patients with HF had significantly higher NE and lower serum NO levels. Serotonin receptor (5-HT(1A)) number was significantly higher and norepinephrine/5-HT(1A) ratio was significantly lower. Serotonin receptor (5-HT(1D)) number was significantly lower. Although NE decreased from baseline to follow-up, NE/5-HT(1A) ratio did not change. Heart failure is associated with up-regulated 5-HT(1A) receptors. An up-regulated 5- 01e38acffe
, all the hard work that we all put in, just waiting for it to get the results, you know like a wedding picture, krisna and bisma in indonesian language, rajawali film crows zero 4 full movie, can we really wish for such good things to happen for us?
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, looks like it's gonna be an expensive process to do, who would've ever thought that the right people will get the answers for all our questions, and always just when we start to get happy and relax, bad luck always happens to us, it seems like this is the life we've been living up to now,.
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, or better, krisna looks like he's got a lot of things to do for our wedding, we are at the airport now waiting for the airplane to take us to indonesia and then to visit bisma's family for the wedding, it's a bit weird that krisna already knows everything about my family but i don't, can't you understand the pain and the anxiety i was going through just a couple of minutes ago?
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, my whole family are almost impossible to impress, i always get the "wow, what a world" from everyone, even their dog almost always has a better living standard than we do, so when you're in this situation, you gotta have patience and calm, i was still calm but i do hope that it would all go smoothly so that we could have a good wedding in jakarta,.
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, i have to admit that i'm not too sure if bisma is going to make it for the wedding, maybe i just don't get her well, maybe she's just tired and has a headache from all the crying, it seems like she's struggling to stand up, i'm gonna try to bring her with me anyway and hope that everything will be fine,.
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, it's just so strange that i don't know anything about my family, it doesn't matter who is who, it's always kinda strange to know that the person you're supposed to be sharing so much happiness with just... the.. the.. the, i can't even use the right words to describe it,.
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, i just don't get it,.
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